| Skippy | One who moves with light leaps. |
| Slav | Person from Slavic countries or cultures. |
| Slave | A person held in forced service. |
| Smiley | Laughing, Happy |
| Smoke | Visible vapor from a burning fire. |
| Smokey | Resembling Smoke, a Smoky Haze |
| Snyder | One who works as a local tailor. |
| Sojin | Korean name meaning 'wisdom' or 'intelligence'. |
| Soldier | A person serving in an army. |
| Somar | One who is born in summer. |
| Sonn | A variant of the name John. |
| Sono | A name meaning sound or tone. |
| Sorab | Famous Persian Prince, Illustrious |
| Spanky | One who is Outspoken or Stubborn |
| Sparky | Giving off Sparks |
| Spelman | English surname meaning 'blacksmith' or 'metalworker'. |
| Spider | Resembling the Arachnid |
| Spyder | Resembling the Arachnid |
| Stancil | Derived from stone clearing. |
| Stanmore | From the stony moorland. |
| Starlin | A bird of the starling kin. |
| Stefen | Wreath, Crowned |
| Stefin | Variant of Stefan, meaning 'crown' or 'garland'. |
| Stelio | Derived from the Greek star. |
| Stephin | A crown or garland of honor. |
| Stergios | Greek name meaning 'watchful' or 'vigilant'. |
| Stev | A short form of the name Steven. |
| Stevin | A variant meaning the crowned. |
| Stewan | Derived from Stephen, meaning 'crown' or 'garland' |
| Stiv | Short form of Steven, meaning 'crown' or 'garland' |
| Stiven | Scottish variant of Stephen, meaning 'crown' or 'garland' |
| Sumo | Japanese term for a professional wrestler, meaning 'strong' |
| Suneil | A young man like the sun. |
| Sut | Short form of Stuart, meaning 'strong and steadfast' |
| Suzi | Variant of Susan, meaning 'lily' or 'pure' |
| Swan | Symbolic of elegance and refinement, often associated with beauty |
| Sway | To move with gentle rhythm. |
| Sylver | Silver-haired, Silver |
| Sabalan | Mountain, strong |
| Sabiqin | Early riser, pioneer |